Pseudotumor cerebri, also known as idiopathic intracranial hypertension (IIH), is a disorder characterized by increased intracranial pressure (ICP) of unknown cause that predominantly affects obese women of childbearing age 2017-10-24 15:57:39-08:00 Tue reinstated sections Infliximab and Rituximab whose text was admixed with citation When the disease manifests in the eye or orbit, it is referred to as IgG4-related ophthalmic disease (IgG4-ROD), which most commonly causes painless swelling of the lacrimal gland (s). Other commonly affected parts of the eye and orbit include the extraocular muscles, orbital fat, infraorbital nerve, eyelid, and the nasolacrimal duct system
ORBITAL INFLAMMATORY SYNDROME (OIS) or ORBITAL INFLAMMATORY PSEUDOTUMOR Inflammation of the orbital contents (i.e., orbital inflammatory syndrome or OIS) including the extraocular muscles, orbital fat, or orbital optic nerve can occur in association with systemic autoimmune disorders . Ocular adnexal lymphoma (OAL) is a localized form of systemic lymphoma affecting the orbit, the lacrimal gland, the lids and/or the conjunctiva. It comprises 6-8% of orbital tumors, and 10-15% of adnexal lesions Idiopathic orbital inflammatory syndrome, also known as orbital pseudotumor, was first described by Gleason in 1903 and by Busse and Hochhmein. It was then characterized as a distinct entity in 1905 by Birch-Hirschfeld Orbital pseudotumor is a benign intraorbital process confined to the orbit but extra orbital involvement can occur. It is among the 3rdmost common orbital diseases along with thyroid orbitopathy and lymphoproliferative disorder and accounts for 5-10% of orbital processes
Orbital cavernous venous malformation (cavernous hemangioma) is a benign, noninfiltrative, slowly progressive vascular neoplasm composed of endothelial-lined spaces surrounded by a well-delineated fibrous capsule. It is the most common benign neoplasm of the orbit in adults Moon WJ, Na DG, Ryoo JW, et al. Orbital lymphoma and subacute or chronic inflammatory pseudotumor: differentiation with two-phase helical computed tomography. J Comput Assist Tomogr. 2003;27(4):510‑516. Mottow-Lippa L, Jakobiec FA, Smith M. Idiopathic inflammatory orbital pseudotumor in childhood II. Results of diagnostic tests and biopsies Orbital pseudotumor represents the second most common inflammatory disorder of the orbit in childhood and may present with unilateral or bilateral proptosis of explosive onset with restriction of ocular motility Sphenoid Wing Meningioma. Squamous Carcinoma of the Eyelid. Squamous Cell Carcinoma of the Orbit and the Adnexa. Stye. Subepidermal Calcinosis. Subperiosteal Hematoma. Superior transverse ligament (Whitnall's ligament) Suspensory ligament of the eye (Lockwood's ligament) Symblepharon An orbital inflammatory pseudotumor is an inflammatory reaction in the orbital tissues that surround the eyes. It is a chronic condition that acts much like a brain tumor. Unlike a tumor, however, the pseudotumor does not spread and does not invade nearby tissues. It will, however, compress nearby structures
Orbital pseudotumor is typically characterized by the rapid development of pain, proptosis, and swelling around the eye and orbit in adults. Ultrasound and computed tomographic (CT) scanning typically shows a diffuse infiltration of the orbit, an inflammation of the eye wall (sclera), and/or T-sign (with the optic nerve) Idiopathic orbital inflammation (IOI), also known as orbital pseudotumor and non-specific orbital inflammation, is an idiopathic inflammatory condition that most commonly involves the extraocular muscles. Less commonly there is inflammatory change involving the uvea, sclera, lacrimal gland, and retrobulbar soft tissue Orbital pseudotumor, also known as orbital inflammatory pseudotumors (OIP), idiopathic orbital inflammation (IOI), orbital inflammatory syndrome (OIS), idiopathic orbital inflammatory pseudotumor (IOIP), or nonspecific orbital inflammation (NSOI) is a benign, space-occupying, and non-infectious inflammatory condition of the orbit but may extend in the peri-orbital area
Orbital myositis (OM) is relatively rare but is the next most common cause of extraocular muscle (EOM) disease after thyroid-associated orbitopathy (TAO). 1, 2 It typically presents as idiopathic acute onset, painful diplopia in young adult females, with inflammation of a single EOM, and usually responds to a course of oral corticosteroids Noninfectious causes of orbital inflammation and proptosis (eg, thyroid-related ophthalmopathy, orbital pseudotumor, and lymphoma) should be considered in both adults and children (Table 4). In pediatric patients, rhabdomyosarcoma, leukemia, metastatic neuroblastoma, and histiocytic disorders should be included in the differential diagnosis Left orbital cellulitis secondary to penetrating dog bite. Swelling and erythema of tissues surrounding the orbit AND: Proptosis. Chemosis. Globe displacement. Limitation of EOM. Pain with eye movements. Double vision. Decreased visual acuity
.e. orbital adnexal MALT lymphoma (OAML)): 50-78% of cases in Western nations, and up to 90% of cases from Japan and Korea 1. It is unclear, however, if MALT exists normally in the conjunctiva of the eye, or whether it represents. Idiopathic Inflammatory Pseudotumor (Orbital Pseudotumor) Orbital pseudotumor is an idiopathic orbital inflammatory process that typically presents clinically with an acute onset of pain, swelling, symptoms (e.g. nasal discharge or stuffiness), pain over sinuses, fever, lethargy, recent periocular trauma or [eyewiki.aao.org] English. Language
An orbital hemorrhage and its relationship to the globe and other orbital structures can be assessed with a CT scan of the orbits (Fig. 2). Contrast is not required for the scan. Laboratory studies, including a CBC to check for hemoglobin and platelet levels, prothrombin time, partial thromoboplastin time, coagulant response time and a factor. Thyroid-associated orbitopathy (or thyroid-associated ophthalmopathy) is the most common cause of proptosis in adults and is most frequently associated with Graves disease.On imaging, it is characterized by bilateral and symmetrical enlargement of the extraocular muscle bellies. The typical distribution is inferior rectus > medial rectus > superior rectus, with sparing of their tendinous. Acute dacryoadenitis is most commonly due to viral or bacterial infection. Common causes include mumps, Epstein-Barr virus, staphylococcus, and gonococcus . Chronic dacryoadenitis is usually due to noninfectious inflammatory disorders. Examples include sarcoidosis, thyroid eye disease, and orbital pseudotumor DISCUSSION. The differential diagnosis in this case includes cellulitis, particularly preseptal or orbital cellulitis, sarcoidosis, thyroid ophthalmopathy, rheumatologic disorders, idiopathic orbital inflammatory syndrome (IOIS) (also known as orbital pseudotumor), metastatic disease (particularly with the patient's history of breast cancer), and tumors, including neuroblastoma. Such a clinical presentation may be seen with tumors of the orbit,46 orbital pseudotumor,38 thyroid eye disease, orbital cellulitis or myositis.38 Isolated Sixth Nerve Palsy Syndrome The patient who demonstrates only lateral rectus weakness and no historical data to implicate a specific etiology, is categorized as having isolated sixth nerve.
Orbital -e.g. Tumor, Pseudotumor, EOM Restriction: Graves Ophthalmopathy, Trauma, Depositions (Amyloid/ MM, WBC) age related degeneration of Orbital Tissues/ Pulley System Cyclo-vertical deviations Systemic -e.g. Myasthenia Gravis Decompensated Strabismus -e.g. Intermittent XT, Monofixation Syndrome, Fixation Switch Diplopi , inflammatory process of the orbit without a known local or systemic cause • Associated with a variety of rheumatologic conditions • Painful • Management • Rheumatology labs • CT • Steroids (mild) • Surgical resection • DDx: • Orbital cellulitis • Thyroid eye diseas Tolosa-Hunt syndrome (THS) is a rare disorder characterized by severe and unilateral headaches with orbital pain, along with weakness and paralysis (ophthalmoplegia) of certain eye muscles (extraocular palsies).. In 2004, the International Headache Society provided a definition of the diagnostic criteria which included granuloma
Nonspecific orbital inflammation (orbital inflammatory pseudotumor), EyeWiki, on-line. Publish Year. 2012. Journal. A Unique Association of Granuloma of the Lower Eyelid to Prior Trauma, Ophthalmic Plastics & Reconstructive Surgery, e87-e88. Peer Reviewed. Yes. Publish Year. 2011. Journal Nonspecific orbital inflammation (orbital inflammatory pseudotumor), EyeWiki, on-line. Publish Year. 2012. Journal. A Unique Association of Granuloma of the Lower Eyelid to Prior Trauma, Ophthalmic Plastics & Reconstructive Surgery, e87-e88. Publish Year. 2011. Journal
Ocular manifestations of lupus are fairly common, may be the presenting feature of the disease and can be sight-threatening. Almost any part of the eye and visual pathway can be affected by inflammatory or thrombotic processes. Ocular pain and visual impairment require urgent assessment by an ophthalmologist Trochleitis is inflammation of the superior oblique tendon trochlea apparatus characterized by localized swelling, tenderness, and severe pain. This condition is an uncommon but treatable cause of periorbital pain. The trochlea is a ring-like apparatus of cartilage through which passes the tendon of the superior oblique muscle. It is located in the superior nasal orbit and functions as a.
Orbital pseudotumor also known as Idiopathic Orbital Inflammatory Syndrome )IOIS( is is an uncommon disorder characterized by non- neoplastic, non-infective, space occupying orbital infiltration with inflammatory features. The process may preferentially involve any or all of the orbital soft tissues. 16 Optic neuropathy is damage to the optic nerve from any cause. Damage and death of these nerve cells, or neurons, leads to characteristic features of optic neuropathy. The main symptom is loss of vision, with colors appearing subtly washed out in the affected eye. On medical examination, the optic nerve head can be visualised by an ophthalmoscope Swelling, tenderness, and erythema of eyelids and superficial tissues surrounding the orbit. +/- fever. Lack of : Proptosis. Chemosis. Globe displacement. Limitation of eye movements. Pain with eye movement. Double vision • Orbital Pseudotumor • Non-infectious, inflammatory process of the orbit without a known local or systemic cause • Associated with a variety of rheumatologic conditions • Painful • Management • Rheumatology labs • CT • Steroids (mild) • Surgical resection • DDx: • Orbital cellulitis • Thyroid eye disease BINOCULAR DIPLOPI Orbital-pseudotumor Symptom Checker: Possible causes include Tolosa-Hunt Syndrome. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search
Several other inflammatory and infiltrative diseases have been reported to also involve the nasolacrimal drainage apparatus, including but not limited to sarcoidosis (approximately 2-8% of cases , idiopathic orbital inflammation (orbital pseudotumor), IgG4-related ophthalmic diseases , and Sjögren syndrome Finally, compression due to Grave's disease, orbital lesions, and trauma can cause optic disc oedema, as well as the hereditary Leber neuropathy . Many of the situations included in the differential diagnosis are extremely rare in children and seldom present by isolated unilateral optic disc oedema Pseudotumor cerebri (SOO-doe-too-mur SER-uh-bry) occurs when the pressure inside your skull (intracranial pressure) increases for no obvious reason. It's also called idiopathic intracranial hypertension. Symptoms mimic those of a brain tumor. The increased intracranial pressure can cause swelling of the optic nerve and result in vision loss Idiopathic intracranial hypertension. Dr Bahman Rasuli and Dr Paresh K Desai et al. Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri, is a syndrome with signs and symptoms of increased intracranial pressure but where a causative mass or hydrocephalus is not identified. On this page
Clinical Features. Bilateral dacryoadenitis: erythema and edema are greatest over the lateral one-third of the upper eyelids. Chemosis and injection of the sclera. Unilateral pain, redness, swelling, pressure in orbital supratemporal area. Rapid onset, hours to days. Chronic form > 1 mo Orbital cellulitis must be differentiated from other diseases that may cause erythema, fever, and edema, such as: Periorbital cellulitis. Endophthalmitis. Severe conjunctivitis. Herpes Zoster Ophthalmicus. Posterior Scleritis. Mucormycosis, Aspergillosis of the globe. M.tuberculosis of the globe Orbital Lymphangioma Pseudotumor Sarcoidosis Lacrimal System Lacrimal System Lacrimal System Anatomy Tearing Evaluation Infections - Lacrimal Treatment of Lacrimal Lacrimal Trauma Lagophthalmos Lagophthalmos The American Academy of Ophthalmology: EyeWiki. Pseudotumor cerebri is a common name for idiopathic intracranial hypertension (IIH), a condition that consists of high pressure in the fluid around the brain. The name pseudotumor cerebri comes from its symptoms (including headache, blurred or double vision, ringing in the ears), which are similar to those of a brain tumor The etiology is not known although it shares histopathogical features with idiopathic orbital pseudotumor. It is an atypical situation and the majority of the medical literature reports cases rather than series of cases. THS cases have been certificated globally and at every ages. Females and male appear to be affected equally
Eye Pain. Eye pain may be described as sharp, aching, or throbbing and should be distinguished from superficial irritation or a foreign body sensation. In some disorders, pain is worsened by bright light. Eye pain may be caused by a serious disorder and requires prompt evaluation. Many causes of eye pain also cause a red eye Factor 1 point 2 points 3 points Total bilirubin (μmol/L) 34 34-50 >50 Serum albumin (g/L) >35 28-35 28 PT INR 1.7 1.71-2.30 >2.30 Ascites Non Congenital oculomotor apraxia. Epicanthal folds. Convergence or accommodative excess. Orbital pseudotumor. Grave disease. Ocular anomalies commonly associated with Duane syndrome. Dysplasia of the iris stroma. Papillary anomalies. Cataracts However, orbital pseudotumor is seldom considered in the differential diagnosis of childhood uveitis. [ncbi.nlm.nih.gov] Differential diagnosis of granulomatous uveitis with orbital inflammation are discussed. [ncbi.nlm.nih.gov] [eyewiki.aao.org] It can cause: a high temperature (fever) night sweats. Not all abduction deficits are cranial nerve VI palsies. Mimickers are orbital lesions, medial wall fractures, Duane syndrome, thyroid-associated orbitopathy, myasthenia gravis, and spasm of the.
Canaliculitis is a rare condition that affects individuals over the age of 50 years. It is characterised by bacterial or fungal infections within the canaliculi and the formation of concretions that are rich in sulphur. Treatments can include topical antibiotics and drainage, though in some cases surgical treatment could be required optic atrophy. Frequent questions. Medical Information Search. Neuritis 14. However, optic atrophy can occur after a bout of optic neuritis, or even in the partner (uneffected) eye over time.(healthtap.com)Aggressive treatment of the underlying ms is the only way to try to prevent flares of optic neuritis and resultant optic atrophy.(healthtap.com)I have optic neuritis from ms
Chemical burns 2. Radiation B. Orbital -1. Retrobulbar tumors 2. Thyroid eye disease 3. Pseudotumor 4. Phlebitis C. Cavernous sinus thrombosis D. Jugular vein obstruction E. Superior vena cava obstruction F. Pulmonary venous obstruction II. Arteriovenous fistulas A. Orbital B. Intracranial-1. Carotid-cavernous fistula 2. Dural fistula 3. Venous. Pseudotumor Cerebri (Idiopathic Intracranial Hypertension). In: Questions And Answers In Neuro-Ophthalmology A Case-Based Approach. World Scientific Publishing Company: Hackensac, NJ, 49-62, 2014. Spitze A, Pruitt C, Al-Zubidi N, Yalamanchili S, Lee AG. Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) The Tolosa-Hunt syndrome is caused by an inflammatory process of unknown etiology. On histopathology, there is a nonspecific inflammation of the septa and wall of the cavernous sinus, with a lymphocyte and plasma cell infiltration, giant cell granulomas, and proliferation of fibroblasts [ 2,3 ]. The inflammation produces pressure and secondary.
Overview. Canalicular lacerations are breaks (interruptions) in the normal tear duct drainage system. If not repaired promptly, tearing will usually lead to. This systems originates with the puncta (there is one in both the upper and the lower eyelid) and is a conduit for tears to travel from the eyelid through the nasolacrimal sac into the nose M. Tariq Bhatti, M.D., is a neuro-ophthalmologist. His clinical focus includes: Providing care for patients with visual disorders related to neurological causes. Complex coordination of care and diagnosis with other specialties such as rheumatology, neurosurgery and otolaryngology. Identifying challenging eye movement, optic nerve or retinal. Atlas of Oculoplastic and Orbital Surgery. Informa Healthcare; 2007. Phillips ME, Marzban MM, Kathuria SS. Treatment of thyroid eye disease. Curr Treat Options Neurol. 2010 Jan. 12 (1):64-9. . Shields AJ, Shields CL, Scartozzi R. Survey of 1264 patients with orbital tumors and simulating lesions: the 2002 Montgomery Lecture, Part 1 Summary. Cranial nerve palsy is characterized by a decreased or complete loss of function of one or more cranial nerves. Cranial nerve palsies can be congenital or acquired. Multiple cranial neuropathies are commonly seen in lesions caused by tumors, trauma, ischemia, and infections.While a diagnosis can usually be made based on clinical features, further investigation is often warranted to. Orbital subperiosteal hemorrhage (SpH) is a rare cause of spontaneous proptosis, which results most commonly from direct trauma but also from increased central vascular congestion following valsalva, weightlifting, emesis, or scuba diving.(1-4) Additionally, SpH may result from periorbital inflammation (eg, sinusitis, orbital cellulitis.
Benign intracranial hypertension [pseudotumor cerebri] H01.121 - H01.129: Discoid lupus erythematosus of eyelid: H20.821 - H20.829: Vogt-Koyanagi Syndrome: H30.001 - H31.9: Chorioretinal inflammations, scars, and other disorders of choroid: H32 [B39.4 also required] Chorioretinal disorders in diseases classified elsewhere [retinitis] H33.001 - H3 Preseptal cellulitis is a common infection of the eyelid and periorbital soft tissues that is characterized by acute eyelid erythema and edema. This bacterial infection usually results from local spread of an adjacent sinusitis or dacryocystitis, from an external ocular infection, or following trauma to the eyelids (see the image below)
Pseudotumor of the orbit: Patients with this condition may present with ptosis due to inflammation and edema of the eyelid. Pseudoptosis: Less tissue in the orbit (eg, unilateral smaller eye, fat atrophy, blowout fracture) produces the appearance of ptosis secondary to the decreased volume of orbital contents Orbital pseudotumor is the third most common primary tumor of the orbit and a common cause of unilateral proptosis in adults (, 32 33) (, Fig 7) It constitutes about 6% of all orbital lesions; Orbital pseudotumor has no sex or race predilection and can develop in patients of any age, although it most frequently occurs in middle-aged individuals The choice largely depends on personal experience because of the limited evidence in this field. In the author's view, if a first course of glucocorticoids provides a suboptimal response, a second course of intravenous (or oral) glucocorticoids associated with orbital radiotherapy should be given
In orbital cellulitis, inflammation and/or an orbital abscess can displace the globe, often pushing it forward or outward which is called proptosis. The presence of proptosis is a medical emergency to evaluate for compartment syndrome. The eyelids can be swollen and in severe cases swollen shut A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text